Research Summary
Our research aims to tackle emerging challenges in biomedical diagnostics related to infectious viral diseases, early prediction of diabetic disorders and associated kidney diseases, and biophysical studies of cancer protein-protein interactions and small molecule inhibitors. Our ongoing projects include the following:
(i) Developing multiplex biosensors for detecting large and small-molecule analytes in practical sample matrices.
(ii) Creating nano-bioarrays for evaluating molecular therapeutic and toxicity properties.
(iii) Developing low-cost paper devices for biomarkers of diabetes and diabetes-related kidney disease.
(iv) Creating non-toxic wearable sensors.
Incoming students to our research group will be able to establish their professional and career development and make pioneering contributions to state-of-the-art biosensor designs, including optical, electrochemical, paper, and wearable approaches. This will involve quantitative nano-surface chemistry, immobilization of desired molecules, reliable detection with sensitivity, specificity, accuracy, and a wide dynamic range on real sample matrices such as blood, serum, urine, saliva, interstitial fluid, food, and environmental water samples. Our target molecules are proteins, hormones, oligonucleotides, antibodies, drugs, and other small molecule analytes.
Our laboratory has a successful track record of achievements and publications from our former and current Ph.D. graduates, undergraduate researchers, and postdocs (2012-present). They have secured their long-term career goals in academia and industry.
We are committed to continuing our passion for solving biomedical/biocatalysis/bioenergy problems that address societal needs presently and in the future. Our laboratory is dedicated to developing a strong STEM workforce, as evidenced by our group's ongoing and past accomplishments.